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A case of primary neuroendocrine breast carcinoma that responded to neo-adjuvant chemotherapy
null
《医学前沿(英文)》 2015年 第9卷 第1期 页码 112-116 doi: 10.1007/s11684-014-0345-z
Primary neuroendocrine breast carcinoma (NEBC) is a very rare type of breast cancer. Two characteristic biomarkers, namely, CgA and Syn, should be immunohistochemically detected to diagnose NEBC. In this study, a 43-year-old woman with a large mass of 8.3 cm × 2.9 cm in her right breast was reported. The patient was pathologically diagnosed with NEBC after specific markers, including CgA and Syn, as well as few differential markers, such as CK7, ER, PR, C-erbB-2, NSE, and E-cadherin, were immunohistochemically detected. The patient showed a remarkable response to four cycles of neo-adjuvant chemotherapy (partial response based on RECIST criteria) and sequentially underwent modified radical mastectomy. Moreover, the diagnosis and treatment of NEBC based on this case and available related literature were discussed.d literature were discussed.
Influence of the adjuvant therapy on the survival of patients with stage II pancreatic carcinoma
Xi-Yan WANG, Hai-Jun LI, Dong YAN, Hao WEN, Shu-Yong PENG,
《医学前沿(英文)》 2010年 第4卷 第4期 页码 430-435 doi: 10.1007/s11684-010-0700-7
《医学前沿(英文)》 2023年 第17卷 第1期 页码 93-104 doi: 10.1007/s11684-021-0892-z
关键词: chemotherapy cervical cancer lymph node metastasis concurrent chemoradiotherapy quality of life
Adjuvant treatment strategy after curative resection for hepatocellular carcinoma
Wei Zhang, Bixiang Zhang, Xiao-ping Chen
《医学前沿(英文)》 2021年 第15卷 第2期 页码 155-169 doi: 10.1007/s11684-021-0848-3
关键词: hepatocellular carcinoma adjuvant treatment hepatic resection recurrence
Hudan Pan, Yanfang Zheng, Zhongqiu Liu, Zhongwen Yuan, Rutong Ren, Hua Zhou, Ying Xie, Liang Liu
《医学前沿(英文)》 2019年 第13卷 第5期 页码 564-574 doi: 10.1007/s11684-018-0676-2
关键词: rheumatoid arthritis traditional Chinese medicine pharmacological mechanism metabolism adjuvant-induced arthritis omics analysis
《化学科学与工程前沿(英文)》 2022年 第16卷 第6期 页码 973-984 doi: 10.1007/s11705-021-2123-1
关键词: pickering emulsion vaccine adjuvant alum-stabilised emulsion oleic to linoleic acid ratio stability
How to judge the association of postmenopausal hormone therapy and the risk of breast cancer
Ling XU
《医学前沿(英文)》 2010年 第4卷 第3期 页码 290-293 doi: 10.1007/s11684-010-0093-7
关键词: breast cancer postmenopausal hormone therapy unopposed estrogen therapy combined estrogen-progestin therapy
Particle therapy for cancers: a new weapon in radiation therapy
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《医学前沿(英文)》 2012年 第6卷 第2期 页码 165-172 doi: 10.1007/s11684-012-0196-4
Particle irradiation started to draw attention in the past decade and has now become a hotspot in the radiation oncology community. This article reviews the most advanced developments in particle irradiation, focusing on the characteristics of proton and carbon ions in radiation physics and radiobiology. The Bragg peak of physical dose distribution causes proton and carbon beams to optimally meet the requirement for cancer irradiation because the Bragg peak permits the accurate concentration of the dose on the tumor, thus sparing the adjacent normal tissues. Moreover, carbon ion has more radiobiological benefits than photon and proton beams. These benefits include stronger sterilization effects on intrinsic radio-resistant tumors and more effective killing of hypoxic, G0, and S phase cells. Compared with the most advanced radiation techniques using photon, such as three-dimensional conformal radiation therapy and intensity-modulated radiation therapy, proton therapy has yielded more promising outcomes in local control and survival for head and neck cancers, prostate carcinoma, and pediatric cancers. Carbon therapy in Japan showed even more promising results than proton therapy. The local controls and overall survivals were as good as that treated by surgery in early stages of non-small cell lung cancer, hepatocellular carcinoma, prostate carcinoma, and head and neck cancers, especially for such highly resistant tumors as melanoma. The non-invasive nature of particle therapy affords more patients with chances to receive and benefit from treatment. Particle therapy is gradually getting attention from the oncology community. However, the cost of particle therapy facilities has limited the worldwide use of this technology.
关键词: radiation therapy particle therapy proton carbon cancer
Passive antibody therapy in emerging infectious diseases
《医学前沿(英文)》 doi: 10.1007/s11684-023-1021-y
关键词: SARS-CoV-2 COVID-19 convalescent plasma hyperimmunoglobulin neutralizing monoclonal antibodies
mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?
Shi-Yong Sun
《医学前沿(英文)》 2021年 第15卷 第2期 页码 221-231 doi: 10.1007/s11684-020-0812-7
关键词: mTOR cancer therapy resistance GSK3 protein degradation E3 ubiquitin ligase PD-L1
Targeted therapy of desmoid-type fibromatosis: mechanism, current situation, and future prospects
Zhen Wang, Jianhui Wu, Xiuyun Tian, Chunyi Hao
《医学前沿(英文)》 2019年 第13卷 第4期 页码 427-437 doi: 10.1007/s11684-018-0672-6
关键词: targeted therapy desmoid-type fibromatosis tyrosine kinase inhibitor γ-secretase inhibitor
Hydroxyl radical-involved cancer therapy via Fenton reactions
《化学科学与工程前沿(英文)》 2022年 第16卷 第3期 页码 345-363 doi: 10.1007/s11705-021-2077-3
关键词: hydroxyl radical Fenton catalyst hydrogen peroxide cancer therapy
Progress in systemic therapy for triple-negative breast cancer
Hongnan Mo, Binghe Xu
《医学前沿(英文)》 2021年 第15卷 第1期 页码 1-10 doi: 10.1007/s11684-020-0741-5
关键词: triple-negative breast cancer immunotherapy targeted therapy
Translational medicine promising personalized therapy in oncology
Yi-Xin ZENG, Xiao-Shi ZHANG, Qiang LIU,
《医学前沿(英文)》 2010年 第4卷 第4期 页码 351-355 doi: 10.1007/s11684-010-0320-2
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 2144-2155 doi: 10.1007/s11705-023-2362-4
关键词: copper sulfide nanoparticles chemodynamic therapy photothermal therapy carbon dots silica nanoparticles
标题 作者 时间 类型 操作
A case of primary neuroendocrine breast carcinoma that responded to neo-adjuvant chemotherapy
null
期刊论文
Influence of the adjuvant therapy on the survival of patients with stage II pancreatic carcinoma
Xi-Yan WANG, Hai-Jun LI, Dong YAN, Hao WEN, Shu-Yong PENG,
期刊论文
Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage
期刊论文
Adjuvant treatment strategy after curative resection for hepatocellular carcinoma
Wei Zhang, Bixiang Zhang, Xiao-ping Chen
期刊论文
Deciphering the pharmacological mechanism of Guan-Jie-Kang in treating rat adjuvant-induced arthritis
Hudan Pan, Yanfang Zheng, Zhongqiu Liu, Zhongwen Yuan, Rutong Ren, Hua Zhou, Ying Xie, Liang Liu
期刊论文
Optimising the oil phases of aluminium hydrogel-stabilised emulsions for stable, safe and efficient vaccine adjuvant
期刊论文
How to judge the association of postmenopausal hormone therapy and the risk of breast cancer
Ling XU
期刊论文
mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?
Shi-Yong Sun
期刊论文
Targeted therapy of desmoid-type fibromatosis: mechanism, current situation, and future prospects
Zhen Wang, Jianhui Wu, Xiuyun Tian, Chunyi Hao
期刊论文
Translational medicine promising personalized therapy in oncology
Yi-Xin ZENG, Xiao-Shi ZHANG, Qiang LIU,
期刊论文